M e d i c i n e A ve 2 October is National Breast Cancer Awareness Month when knowledge grows, hope flourishes Thank you to everyone at Genentech. Your passion for innovation keeps hope in full bloom. Genentech AVASTIN "Y Herceptin C.v, 4t.tf.n-ww >r.r.--: no*>«c«ioc< ! Mi / \ t r«»tuIunrab 1 :__________ 1. AGENCY: Flashpoint Medica CREATIVE TEAM: Steve Frederick, Kerry Baker, Liz Blickle, Meaghan Golden CLIENT: Genentech for Breast Cancer Awareness 2. AGENCY: Wishbone/ITP CREATIVE TEAM: Mark McDowell, John Thelian, Stephanie Sorine CLIENT: Meda Pharmaceuticals 1 in cooking journal for etreat football game plan: com p le te 1 year of adjuvant Herceptin therapy One year of adjuvant Herceptin therapy can lower the risk of breast cancer returning' 'Rased on 4 dinteal trials of over 10,000 women who received adjuvant Herceptin therapy. ("Adjuvant therapy" means treatments that are given after surgery to help prevent cancer from returning.) In these studies, women also received usual adjuvant therapies, including chemotherapy with or without radiation and/or hormonal therapy, Who ts Herceptin for? »>er<epi»r; t* approved fw tfw adjuvant Uedsncoi o f H lfV ovefexpravrn :v.v-ftoviftv'r- o: dtive (cfirPR-negairw or w h<^«-r«< brftast • <ovw ppfe? Iv* used s*\» cSbV'-m? w.-ws * p>:tofa ttettAKAi ctgimert intfexfii^j dbxon&Cta ai we»fb<y par ktaxe? <?r d&et&vei ♦Wrtfedoe &wel endcarfcoplatso As 6 agt/rrt fdtewihg muuinwcltfity therapy What important safety information should I know about Herceptin? Herceptin treatment can result in heart problems, including those without symptoms {reduced heart function) ami those with symptoms fcongestive hear! failure). fl«* risk and seriousness of these heart problems were highest in (teople who received bolt) Hercc-jUmand a certain type of chemotherapy(^nthracycfioe). Ybur doctor -will stupor strongly consider stopping Herceptin if you have a significant drop in your heart function. y&j t ocesptiJu:*id. t *mortdMCdlot decreasedheal furetoft beforeyoufyst dose<;t stv?<epjei. andfrequentlyduring?l«rimeyowarerc<o«wxj .wd after yixer w t <fep» of tfsrcepwi it ^ irwst pwnaswtfy« slop roaus.i odoetoik-at preC.Sefl;\ youstouW b e monAoredRXtec inwe studywithH&ceptu: ami c tasnr, pocof chemotherapy. mi uwdsxfuateblo dsuplytodieJwart occurs Some patients Havehadserious infosk wreacttojn and lung problems fita ?infusion reactions have been reported. In most cases, these reactions occurredduring or wilhm ?4 Hours of referring Herceptin. YamHerceptminfuiion should lie tenHmrjJily stopped i f you have sborlncss of breath or very Jowblood pressure. Your decor wHf mooltw yoo until these symptoms qo away. If you have a severe allergic reaction, swelling, lung problems i uflawwtion of the lung, oj severe shortness of breath, your doctor rrv>yneed to completely stop your Herceptin treatment. Vionfiousgcrl Jaw hilefcta dcel spo lsas ocMtedwithchemotherapyft» ly. wt i- *eicept. <i cati causel owantnkrtic fty<dlew*andha«ntothefeus aIko t«dcwbya pregnant woman. ftie most common stele$ffec<s associated with ner<t?ptx>were nausea, voonting. mfus&n luaciiisn, rlwitbea. >iuV.ttons. lotre.swd cough i'c-atferhe, fatigue, shfifioessof breath, rash, tev>white attd rsd WoodcoSs, mkI muscle paki Becauseeveryone ¥, dif erent, r?isnot pos iblernprecfti what ef erisany«*■personwifi haveifyouIwvetpiest»nsor concerns abw: sideeftatv, uiktoyourdoctor YouareWKOvcragecf t oreport negalicesrek*ef ects ot pt evt pt cndrugs t othe(i>A Vtsl vaw/ HmCfcrvfljwfswatch, or <3$l -8>X*-F&A-l$38 ■'Rvtv-sabnext ppo»* fpr fotieM 8rief Summary whic hs>Judes smpnda11 -doty inKKmaiwn you :.}:<»>.dc} iuw.v almot Hertepiuc X Herceptin* trastuzumab For the woman who has been diagnosed with HER2+ breast cancer her plan: Learn how to make a chocolate souffle class. Host a family reunion. Keep aw an entire year. Submit a short story tc See her daughter get married.Sho^ at a local gallery. See her s o o ^M law school. Go tc a yoga^B ^H [H in India. View the v e r y t o p ^ j j Grand Canyon...from th tiP bottom her granddaughter hov^^,|o knitjM own boss.Beautify the vatm *X-y*r? koi pond. Learn to speak French-^ an accent. Cheer for her favorite team when they win the big game passport with stamps from arounc fa magazine, her paintings -mm' M , ,, W fof the without Rill her the world. 180
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