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T h e 6 0 ' s Tylenol or aspirin: which analqesic for the ulcer patient? 1 Client: Bristol. Agency: Sudler & Hennessey. AD and Copy: Herb Lubalin (1960s). 2 Client: Roche. Agency: McAdams. AD: Jerry Philips. Photog..Gerald Hochman. Copy: John Kallir (1960). 3 The most successful campaign in the history of medical advertising began in 1965 with fractional b/w pages in a few medical journals.Safer than aspirin, but just as effective ... an obvious positioning in retrospect, but it had never been tried before. As Tylenol sales responded, budgets were increased, but the product continued to be promoted exclusively to physicians and nurses from 1965 to 1975. By the time consumer media were added to the mix, Tylenol had become the leading non-Rx analgesic! Client: McNeil. Agency: Kallir Philips, Ross. AD: Jerry Philips.CoPvr Warren Ross. (1965). 4 Client: Bristol. Agency: Sudler & Hennessey. AD: Herb Lubalin. (1960s) "Aspirin...plays a significant part in exacerbation of ulcer symptoms and is at least a contributory cause in one in eight cases of haematemesis... Acetaminophen "...should therefore be used in preference to aspirin as a pure analgesic in all cases of peptic ulcer."* On the many occasions when your knowledge and judgment are colled on in the selection of on onalgcs<c, remember thot TvtfNOi—while just os effective os aspirm —often odds on importont margin of safety. Precautions and Adverse ffeocfions If a rare sensitivity reaction occurs, the drug should be stopped. Tyi{noi has rarely been found to produce any side effects. Supplied: Scored, white tablets of 325 mg. in packages of 12 ,24,100.250. A/so ovoi/ob/c TntNOt* with Codeine Tablets, containing codeine phosphate 7.5 mg. IH gr.) No. 1, 15 mg. (l&gr.) No. 2 .30 mg. (V5gr.) No. 3, or 60 mg. (1 gr.) No. 4 (Worning—Moy be habit forming)—in addition to ocetaminophen 300 mg. «nbottles of 100. I. Muir, A., ond Cossor, I. A.-. Brit. Med. J. 2-.7-12 (July 2) 1955. 2. Craddock, D.: Practitioner 189:>92-200 (Aug.) 1962. safer than aspirin...yet just as effective H E T y i e n ° i (acetaminophen] I M cNEIL I m u Ml 678-1 Active throughout the body— In patients of all ages. There are somanyreasons why you can use this penicillin like a broad-spectrum antibiotic 0 Capsules of 250 mg. and 500 mg. for adults; Oral Suspension for infants and children, in 125 mg. and 250 mg. 5 ml. strengths. Polycil- lin-N (sodium ampicillin) for Injection, in vials of 125 mg.. 250 mg.. 500 mg. and 1 Cm. Versatile: a form and potency for every patient initial, single-agent therapy for | » motion, „t many »■*. IV ||V f“| I 11 ft throughout the body in otitis. *• (ampicillin tr,hydrate) tis and in cystitis, urethritis, and CAPSULES pyelonephritis. 1‘olycillin-N (sodium ampicillin), l.M. or I.V., provides bactericidal vvi.ii.t<.k-ri.t«i therapy in bacterial (ampicillin trihydrate) FOR ORAL SUSPENSION Ho toxicity to date-and no risk o( tooth staining. meningitis and septicemia. Many forms and strengths are available, so you can easily prescribe the dosage unit ami route of administration best suited to the severity of infection, size of the patient,.and duration of therapy. Polycillin’ (ampicillin trihydrate) P u lp illin lV (sodium ampicillin) FOR INJECTI0N-I.M./I.V. For prescribing information, sre last page. Bactericidal: bacterial ceils burst - and die. Polycillin (ampicillin trihydrate) is the first oral broad-spectrum antibiotic that is bactericidal not merely bacteriostatic. It interferes with the synthesis of the bacterial cell wall, causing the growing organism to burst and die. Polycillin (ampicillin trihydrate) is simple to use and. unlike the tetracyclines. there is.no risk of tooth staining with any of its forms. Experience has shown that oral and parenteral ampicillin may be given for months, in high doses-even in patients with renal insufficiency.1 However, as with any penicillin, the possibility of allergic reaction should be considered. Polycillin (ampicillin trihvdrate) is a versatile problem-solvcr. Its broad bactericidal action permits Polycillin (ampicillin trihydrate) extends the bactericidal effectiveness of the penicillins over a wide range of pathogenic organisms. It not only works against pneumo-. strepto- and sensitive staphylococcal infections.but its ih rn-o action against many Cram-negative infections is greater than that of tetracycline or chloramphenicol.*-2 Broad-spectrummany significant pathogens are sensitive: 4 51

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