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M e d i c i n e A v e n u e 1 Blinded by depression, groping anxiously for meaning in what he sees as a hopeless, precarious existence, the depressed patient is often emotionally pulled in opposite directions. While his depression is immobilizing him with feelings of withdrawal, lack of interest, and fatigue, the accompanying anxiety keeps him awake nights worrying about the future. For these patients, there is no better tricyclic than Tofranil-PM. In a recent study of anxious depressed patients the quality of sleep and rising time was significantly better with imipramine pamoate group than in an amitriptyline [Elavil | treated group. Other measures of relief were not significantly different. "Ibfranil-PM imipramine pamoate Unsurpassed effectiveness among tricyclics in relieving anxiety, sleep disturbances and other symptoms of depression. 2 Copelessness Tofranil-PM Geigy imipramine pamoate Unsurpassed effectiveness among tricyclics in relieving symptoms of depression. 36

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