M e d i c i n e A v e n u e consultant to Upjohn in 1948, an association that lasted for more than 20 years. His contributions included a new format for professional advertising and two internationally acclaimed exhibits: giant walk-through models of a cell and of the human brain. Advertising managers and creative directors at companies had a strong influence on the character of medical advertising, particularly in the period 1950 to 1970, prior to the delegation of responsibility for advertising to product management at manufacturers. Some of the people who have left their mark on the industry include: Norman Sprei (Squibb); Rollie Noel (Bristol); Robert Devanna, Irwin Lerner and Ira Contant (Roche); John Hogan, Edward Steel (McNeil); Mai Freeman, Frank Mann (Robins); Bud Nelson, (Ortho, Syntex); Richard Truby, Robert Handy (Upjohn); John Spitznagel (Wyeth); Edward Whitney (Pfizer and W-C); Gene McCabe, Thomas Beckett and George DiDomizio (Merck); William Gulick (Bristol, Roche); Toby Wagner (SKF); Robert Beine and William Pratt (Abbott); Audrey Girard (Roerig); Robert Oppenheimer and Austin Daley (Eederle); Bob Baldini and Charlie Hackett (CIBA- Geigy); Clifford Parish (Burroughs Wellcome); and Whitmore Jensen (Ayerst) —J.K But bctorc you fxtjcri* Fertofrana. ptoasc '.cc '.he M prcK'itxrg information nod CJpOCvjUy note CcntraavKdHOW. P:ocau!>oov Wyning. AdrtricRwn-cnsanaCtos^jo Aty^summry of that nformat.cn « «ncJud«l (wo. t^nofrane’anortTync hyQrocNoodp bvfcatens For relief of dcprcuicn. Do no! ute drugs of the W.AOl cUsi with PertQfrane. Hyperpyrctic e r « « or to/erocowAjttive cutset may occur; I., **owan interval of * tea 7 stoys tnrtioi dosage in such patients shoo'd be towand increases shocJd be gradual andcautoutypreserved psvehovs mayoccasionaBt be obso'ved m ictwoohrcoc p unless the ctimcai stuahcn a Precautions: CaretJ suoersvson and r/olcctive me»vjr« (o' potentially suoda! wtk-nt'. are noccvsary DsominuationoMhcfawcrodjunc- t<veuseofasedanvea tranouii-tcrmaybenccesWhat makes a A man? Another woman? Three kids? No kids at all? Wrinkles? You name it. an*oa.-V;<ttorvsma9wi!.si C*fcJu*yobserve rv those receiving thyroid medeetion« Cardio- vascular comp<ca;>sns tmyocardsi intarcbon and arrtyuvrvat) rc poeontm r*v* j.ree they hare occasonaty occurred with mvpraovne. the parent compound Oesiprarrvio may week thepharmacotogc actwitv ol guar*hone and rriateoadrenergo rwonblocking agents Myra been observed duvtg penentM) eonodw K tsondciifvanvre thecaoy. nthcchojivji.7 andmsnegen* AJ-xvs* Reaction I bst ji bedmust accommodation, anorevnt. po Kvat-on nsorrru*. & o.vs<no«. di«mew. he* ache nausea, epgastric distress. and sun ms (*v3jdng photosens'tuation)mayAppear $nt ooserie patents rcqurinQ concomitant vasod U’-ng therapy, particularly during the inm. p*>»« O.rw ad»«rte reaencos mchide tar.n tiornandetsoncrvtatem) OCCWOCCOKOnaHyowl mayreou'e reducedctoiain or dffcontinuenoe o' therapy fta-dv transient eosmepM-.a. sight orvg and investigate Occasion* hormonal ofoccur. »heO<ugs*dutobed>M«if k>rvV»-S bone rnjirort OCf/( trvcrrtWiOOCrvO or 01/pure o' Is she truly depressed? Is that why she lets go in your office? You comfort her. Talk to her. And, if she is depressed, consider Pertofrane. Because in 3 to 5 days she can often begin to cope, work, maybe play, even enjoy. t«cfi*jhoJkJ begrvnntowOOSOS Pv* capyJtr, ot 25 mg. usbofliosof rcrcomt»cie droits cSoase tc Gogy towrmateuticaSs OvaonotGevgyCTxmcalCorporatdo (fat A-dtfey NewYork 10552 Pertofrane* desipramine hydrochloride In depression... when words are not enough 34
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